Online cognitive behaviour therapy for asthma-related anxiety: a randomised controlled trial.

This study evaluated the efficacy of therapist-guided, internet-delivered cognitive behavioural therapy (ICBT) versus treatment as usual plus medical education for reducing asthma-related anxiety.

本研究评估了在治疗师指导下通过互联网进行的认知行为疗法（ICBT）与常规治疗加医学教育相比，在减少与哮喘相关的焦虑方面的有效性。

Methods

A randomised controlled trialwas conducted including 90 adult participants with anxiety related to asthma.

开展了一项随机对照试验，纳入了90名患有与哮喘相关焦虑的成年受试者。

ICBT was therapist-guided and lasted 8 weeks.

ICBT由治疗师指导，并持续了8周。

The primary outcome, the Catastrophising about Asthma Scale, was assessed from pretreatment to the primary endpoint at 16 weeks.

主要结果是哮喘灾难化量表，从治疗前到16周的主要终点进行了评估。

Secondary outcomes included asthma control, avoidance behaviour and quality of life.

次要结果包括哮喘控制、回避行为和生活质量。

Forced expiratory volume in 1 s (FEV1) was collected using a digital spirometer.

使用数字肺活量计收集了一秒钟强迫呼气量（FEV1）。

Results

ICBT demonstrated a significantly larger reduction in catastrophising about asthma than the control group (mean difference -18.53, 95% CI -25.54 to -11.53, p<0.001).

认知行为疗法（ICBT）在减少对哮喘的灾难化思维方面，与对照组相比显示出显著更大的改善（平均差异-18.53，95%置信区间-25.54至-11.53，p<0.001）。

Asthma control, avoidance behaviour, quality of life and other key outcomes improved significantly more in the ICBT group compared with controls.

与对照组相比，ICBT组在哮喘控制、避免行为、生活质量和其他关键结果方面显著改善。

No changes in FEV1 were observed.

未观察到FEV1的变化。

Improvements were sustained at 6 months follow-up.

在6个月的随访中，改善效果得以持续。

Conclusions

ICBT effectively and safely reduces catastrophising about asthma, improves asthma control, avoidance behaviour and quality of life and represents a promising adjunct to routine medical care for patients with asthma complicated by anxiety.

认知行为疗法（ICBT）有效地且安全地减少了对哮喘的灾难化思维，改善了哮喘控制、回避行为和生活质量，对于伴有焦虑的哮喘患者来说，是一种有前景的常规医疗辅助治疗手段。

trial_registration_number

Clinicaltrials.gov (ID: NCT04230369).

临床试验注册 (ID: NCT04230369).