Facial airflow enhances the benefits of exercise training in people with chronic lung disease: a randomised controlled trial.

Stimulation of the trigeminal nerve via fan-to-face (F2F) therapy (facial airflow) can reduce exertional breathlessness and improve exercise endurance in CLD.

通过风扇对脸（F2F）疗法（面部气流）刺激三叉神经可以减少运动性呼吸困难并提高慢性肺病（CLD）患者的运动耐力。

This randomised controlled trialtested the hypothesis that adding F2F therapy to an exercise training programme could enhance the benefits of exercise training on exercise endurance time (EET) and exertional breathlessness in adults with CLD by allowing them to train at higher intensities.

这项随机对照试验测试了这样一个假设：将面对面治疗（F2F）加入到运动训练计划中，能够通过使患者能够进行更高强度的训练，从而增强运动训练对慢性肺疾病（CLD）成人运动耐力时间（EET）和劳累性呼吸困难的益处。

Methods

23 participants with COPD (n=19) or interstitial lung disease (n=4) were randomised to 5 weeks of thrice weekly supervised exercise training with (F2F; n=12) or without (no fan (NF); n=11) facial airflow.

23名患有慢性阻塞性肺疾病（COPD）（n=19）或间质性肺疾病（n=4）的参与者被随机分配到每周三次、为期5周的监督下运动训练，其中一组接受面部气流（F2F；n=12），另一组不接受（无风扇（NF）；n=11）。

Primary outcomes were baseline to post-exercise training change in EET and isotime breathlessness intensity ratings assessed using constant work-rate cardiopulmonary treadmill exercise testing.

主要结果是基线到运动训练后EET和等时运动呼吸困难强度评分的变化，这些评分是通过恒定工作率的心肺跑步机运动测试来评估的。

Results

Cumulative exercise training volume over the 5-week exercise training programme was similar in the F2F and NF groups, whereas breathlessness intensity ratings were consistently lower across all exercise training sessions in the F2F group.

在为期5周的运动训练计划中，面对面(F2F)组和非面对面(NF)组的累积运动训练量相似，而F2F组在所有运动训练课程中的呼吸困难强度评分始终较低。

Both the F2F and NF groups showed significant increases in EET (mean±sd 7.2±9.1 min, 95% CI 3.0-13.6 min, versus 8.6±8.5 min, 95% CI 6.3-9.0 min, respectively) and decreases in isotime breathlessness intensity ratings (-2.1±1.5 min, 95% CI 0.6-3.2 min, versus -1.5±1.1 min, 95% CI 0.8-4.0 min, respectively) from baseline to post-exercise training, with similar magnitudes of change observed between groups.

面对面（F2F）和非面对面（NF）组在运动训练前后均显示出显著的运动后呼吸困难缓解时间（EET）增加（平均值±标准差分别为7.2±9.1分钟，95%置信区间3.0-13.6分钟，以及8.6±8.5分钟，95%置信区间6.3-9.0分钟）和运动时呼吸困难强度评分的降低（分别为-2.1±1.5分钟，95%置信区间0.6-3.2分钟，以及-1.5±1.1分钟，95%置信区间0.8-4.0分钟），两组间变化幅度相似。

Conclusions

F2F therapy (facial airflow) is a simple, feasible, low-cost, low-resource nonpharmacological approach to reduce exertional breathlessness during an exercise training programme in people with CLD.

面部气流（F2F）疗法是一种简单、可行、低成本、低资源的非药物方法，用于在慢性肺疾病（CLD）患者的运动训练计划中减少运动时的呼吸困难。