Behavioral Support by Ex-Smoking Peers Using Instant Messaging for Smoking Cessation: A Randomized Controlled Trial.

Randomized controlled trial(RCT) evidence is lacking regarding mobile-based behavioral support offered by ex-smoking peers on smoking cessation in community people who smoke.

关于由戒烟的前吸烟者提供的基于移动设备的行为支持在社区吸烟者中对戒烟的影响，缺乏随机对照试验（RCT）证据。

research_question

Is mobile-based behavioral support provided by ex-smoking peers effective in promoting smoking cessation among community people who smoke?

由戒烟同伴提供的基于移动设备的行为支持是否能有效促进社区吸烟人群戒烟？

study_design_and_methods

An RCT was conducted with people who smoked daily under the Hong Kong Quit-to-Win Contest 2021.

在2021年香港戒烟胜利竞赛中，对每日吸烟者进行了一项随机对照试验（RCT）。

All participants received brief smoking cessation advice at baseline.

所有参与者在基线时接受了简短的戒烟建议。

Each participant in the intervention group joined a 3-person chat group of instant messaging apps (eg, WhatsApp), which consisted of the person who smoked, a smoking cessation advisor, and a trained ex-smoking peer who had quit smoking for ≥ 1 year.

干预组的每位参与者加入了一个由即时通讯应用程序（例如，WhatsApp）组成的3人聊天群，该群包括吸烟者、戒烟顾问以及至少戒烟1年以上的训练有素的戒烟同伴。

Personalized behavioral support lasted 3 months through the chat group by ex-smoking peers, including experiences of quitting strategies, coping with withdrawal symptoms, use of smoking cessation services, and encouragement.

个性化的行为支持通过聊天群组由戒烟同伴进行，持续3个月，包括分享戒烟策略、应对戒断症状、使用戒烟服务以及鼓励。

The control group received 6 smoking cessation text messages and follow-up reminders.

对照组收到了6条戒烟短信和后续提醒。

The primary outcome was biochemically validated abstinence at 6 months following intervention initiation.

主要结果是干预开始后6个月的生化验证的戒断。

Analysis was by intention-to-treatusing Poisson regression with robust variance.

分析采用意向治疗分析，使用具有稳健方差的泊松回归。

Results

From June to September 2021, a total of 1,105 participants were randomly assigned to the intervention (n = 553) and control (n = 552) groups.

2021年6月至9月期间，共有1105名参与者被随机分配到干预组(n = 553)和对照组(n = 552)。

At 6 months, compared with the control group, the intervention group showed a nonsignificant increase in biochemically validated smoking abstinence (8.9% vs 6.7%; risk ratio [RR], 1.32; 95% CI, 0.88-1.99) and more usage of smoking cessation services (14.5% vs 10.0%; RR, 1.45; 95% CI, 1.05-2.00).

在6个月时，与对照组相比，干预组在生化验证的戒烟成功率上显示出非显著性的增加（8.9%对比6.7%；风险比[RR]，1.32；95%置信区间，0.88-1.99），并且更多地使用了戒烟服务（14.5%对比10.0%；RR，1.45；95%置信区间，1.05-2.00）。

In the intervention group, participants who engaged in instant messaging support exhibited much more validated abstinence (22.2% vs 4.9%; RR, 4.52; 95% CI, 2.66-7.68).

在干预组中，参与即时消息支持的参与者显示出更高的验证性戒烟率（22.2%对比4.9%；相对风险，4.52；95%置信区间，2.66-7.68）。

interpretation

Behavioral support by ex-smoking peers via instant messaging was shown to be potentially effective and should be improved to increase smoking abstinence.

通过即时消息进行的行为支持，由已经戒烟的同伴提供，显示出潜在的有效性，并应加以改进以增加戒烟的成功率。

clinical_trial_registration

ClinicalTrials.gov; No.: NCT04909320; URL: www.

ClinicalTrials.gov; 编号: NCT04909320; 网址: www.

clinicaltrials

gov.

5年总生存率为75%，95%置信区间为68-82%。