Effectiveness of Health Communication Intervention to Improve Knowledge on Timeliness to Return for Annual Lung Cancer Screening: The Larch Trial.

A health communication intervention was tested to improve patient knowledge, tobacco-related stigma, and self-efficacy in LCS.

测试了一种健康沟通干预措施，以提高患者对LCS的知识、烟草相关的污名化以及自我效能。

research_question

Does additional health communication improve patient knowledge of LCS timeliness?

额外的健康沟通是否能提高患者对肺癌筛查（LCS）及时性的了解？

study_design_and_methods

Trial participants aged 50 to 78 years with a normal LCS scan were randomized to the intervention or control arm.

试验参与者年龄在50至78岁之间，且肺癌筛查（LCS）扫描结果正常，被随机分配到干预组或对照组。

The intervention was delivered 3 weeks following an LCS scan.

干预措施在进行低剂量计算机断层扫描（LCS）后3周实施。

Intervention participants received health communication (print plus video) with 3 key messages to normalize routine LCS; a reminder of when due for screening; and encouraging social connection.

接受干预的参与者收到了包含3个关键信息的健康传播材料（印刷品加视频），旨在使常规LCS正常化；提醒筛查的到期时间；并鼓励社交联系。

Interventions were primarily delivered through the electronic health record patient portal. Eight weeks following the scan, all participants were invited to complete an online or telephone survey about knowledge, tobacco-related stigma, and self-efficacy.

干预措施主要通过电子健康记录患者门户进行。扫描后8周，邀请所有参与者完成关于知识、烟草相关污名和自我效能感的在线或电话调查。

Modified Poisson and linear regression was used to test association of the intervention on secondary trial outcomes, using weights to account for survey nonresponse.

使用修改后的泊松回归和线性回归来测试干预措施对次要试验结果的影响，使用权重来考虑调查的非回应。

Heterogeneity of the intervention effect was tested by using tobacco and LCS histories.

通过使用烟草和低剂量计算机断层扫描（LCS）的历史记录来测试干预效果的异质性。

Results

The survey participation rate was 38.9% with 714 respondents (n = 363 intervention; n = 351 control).

调查的参与率为38.9%，共有714名受访者（干预组n = 363；对照组n = 351）。

Knowledge to return in 1 year improved by 13% in the intervention arm vs the control arm (relative risk, 1.13; 95% CI, 1.05-1.22; P < .001).

干预组与对照组相比，一年内返回的比例提高了13%（相对风险，1.13；95%置信区间，1.05-1.22；P < .001）。

Intervention increased the proportion by 21.9% who knew to return in 1 year from 62.0% to 83.9% (relative risk, 1.35; 95% CI, 1.16-1.58) in first-time screeners but no difference in those screened 2 or more times.

在首次筛查者中，干预组将一年内返回的比例提高了21.9%，从62.0%增加到83.9%（相对风险，1.35；95%置信区间，1.16-1.58），但在两次或更多次筛查者中没有差异。

No other statistically significant differences in knowledge were detected.

未检测到其他统计学上有显著差异的知识点。

In the control arm, both tobacco-related stigma (mean, 13.9; 95% CI, 13.6-14.2) and self-efficacy (mean, 29.0; 95% CI, 28.6-29.4) were high and unchanged by the intervention.

在对照组中，烟草相关的污名化（平均值，13.9；95% 置信区间，13.6-14.2）和自我效能感（平均值，29.0；95% 置信区间，28.6-29.4）都很高，并且没有因干预而改变。

interpretation

A multiformat LCS intervention was shown to improve short-term knowledge of LCS timeliness to return.

一项多格式的肺癌筛查(LCS)干预措施被证明可以提高对LCS及时返回知识的短期了解。

This finding suggests that additional health communication beyond shared decision-making might encourage repeat screening, especially in first-time screeners.

这一发现表明，除了共享决策之外的额外健康沟通可能会鼓励重复筛查，特别是在首次筛查者中。

clinical_trial_registration

ClinicalTrials.gov; No.: NCT05747443; URL: www.

ClinicalTrials.gov; 编号: NCT05747443; 网址: www.

clinicaltrials

gov.

5年总生存率为75%，95%置信区间为70-80%。