DASH-patterned groceries and effects on blood pressure in adults treated for hypertension: the GoFreshRx randomized trial.

In this study, we conducted a randomized clinical trial (GoFreshRx) to test whether local groceries ordered with the assistance of a dietitian to align with the DASH diet might lower BP among Black adult residents of Boston communities with few grocery stores who were being actively treated for hypertension.

在这项研究中，我们进行了一项随机临床试验（GoFreshRx），以测试在营养师的帮助下订购的符合DASH饮食的本地食品，是否可以在波士顿社区中少有超市的黑人成年人居民中降低正在积极治疗的高血压患者的血压。

Individuals whose systolic blood pressure (SBP) was 120 mmHg to <150 mmHg despite active hypertension treatment were randomized either to 12 weeks of weekly home-delivered DASH groceries with dietitian counseling or to receiving three US$500 stipends every 4 weeks.

尽管积极接受高血压治疗，但收缩压（SBP）在120毫米汞柱至<150毫米汞柱的个体被随机分配，要么接受12周每周一次的家庭配送DASH食品和营养师咨询，要么接受每4周三次各500美元的津贴。

The primary outcome was research clinic-measured SBP measured at 3 months.

主要结果是3个月时在研究诊所测量的SBP。

Secondary outcomes were diastolic blood pressure (DBP) and low-density lipoprotein cholesterol (LDL-c) levels.

次要结果是舒张压(DBP)和低密度脂蛋白胆固醇(LDL-c)水平。

Maintenance of health effects was assessed at 3 months after the intervention.

在干预后3个月评估了健康效果的维持情况。

Of 176 participants (mean age 60.1 (s.d., 11.5) years; 80.7% female), 173 were available for SBP measurement at 3 months.

在176名参与者中（平均年龄60.1（标准差，11.5）岁；80.7%为女性），有173人在3个月时可用于测量收缩压（SBP）。

Mean (s.d.) baseline SBP/DBP was 130.5 (7.0)/77.8 (8.9) mmHg.

平均（标准差）基线收缩压（SBP）/舒张压（DBP）为130.5（7.0）/77.8（8.9）毫米汞柱。

At 3 months, SBP changed by -7.0 mmHg in the DASH groceries group and by -2.0 mmHg in the self-directed group (intergroup difference: -5.0 mmHg; 95% confidence interval: -8.0 to -1.9; P = 0.002).

在3个月时，DASH食品杂货组的收缩压（SBP）变化了-7.0毫米汞柱，而自我指导组变化了-2.0毫米汞柱（组间差异：-5.0毫米汞柱；95%置信区间：-8.0至-1.9；P = 0.002）。

Moreover, compared to the self-directed group, 3 months of DASH groceries changed DBP by -1.8 mmHg (-3.6 to -0.1) and LDL-c by -7.0 mg dl-1 (-13.6 to -0.5).

此外，与自我指导组相比，3个月的DASH食品杂货使舒张压（DBP）降低了-1.8毫米汞柱（-3.6至-0.1），低密度脂蛋白胆固醇（LDL-c）降低了-7.0毫克/分升（-13.6至-0.5）。

In prespecified analyses, the beneficial effects of DASH grocery delivery on SBP and DBP were partially maintained 3 months after the intervention had concluded.

在预先设定的分析中，DASH杂货配送对收缩压(SBP)和舒张压(DBP)的有益效果在干预结束3个月后部分得以维持。

Nutrient-targeted grocery ordering appears to be a useful strategy to improve longer-term cardiometabolic health.

针对营养的杂货订购似乎是一种改善长期心脏代谢健康的有用策略。

ClinicalTrials.gov registration: NCT05393232 .

临床试验注册：NCT05393232 .