Mindfulness and Tai Chi for Cancer Health (MATCH) Study: Primary Outcomes of a Preference-Based Multisite Randomized Comparative Effectiveness Trial.

Two mind-body interventions for treating these problems are Mindfulness-Based Cancer Recovery (MBCR) and Tai Chi/Qigong (TCQ).

用于治疗这些问题的两种身心干预方法是基于正念的癌症康复（MBCR）和太极/气功（TCQ）。

However, while both interventions show efficacy compared with usual care, they have never been studied together.

然而，尽管这两种干预措施与常规护理相比都显示出效果，但它们从未一起被研究过。

This trial was the first, to our knowledge, to incorporate innovative design features including patient choice while evaluating two interventions to treat distressed cancer survivors.

据我们所知，这项试验是首次结合创新设计特点，包括患者选择，同时评估两种干预措施来治疗困扰癌症幸存者的。

Methods

A preference-based multisite randomized comparative effectiveness trial design with broad pragmatic inclusion criteria was used.

采用了一种基于偏好的多中心随机比较有效性试验设计，具有广泛的实用纳入标准。

Participants with a preference for either MBCR or TCQ received their preferred intervention, while those without a preference were randomly assigned 1:1 into either intervention.

有偏好的参与者接受了他们偏好的MBCR或TCQ干预，而没有偏好的参与者则被随机分配为1:1接受任一干预。

Furthermore, participants were all randomly assigned 2:1 into immediate intervention or waitlist control.

此外，参与者均按2:1的比例随机分配至立即干预组或等待名单对照组。

Total mood disturbance (TMD) on the Profile of Mood States after intervention was the primary outcome.

干预后在心境状态剖面图上的总情绪困扰（TMD）是主要结果。

Results

Five hundred eighty-seven participants provided baseline data, 75% were female, with an average age of 60.7 years.

共有587名参与者提供了基线数据，其中75%为女性，平均年龄为60.7岁。

Of 12 cancer types, the most prevalent were breast (40.7%), prostate (11.2%), and GI (9.7%) cancers.

在12种癌症类型中，最常见的分别是乳腺癌（40.7%）、前列腺癌（11.2%）和胃肠道癌（9.7%）。

Most had stage 0-II (50.1%) diagnoses, with 17% having more advanced disease.

大多数患者被诊断为0至II期（50.1%），其中17%的患者病情更为晚期。

Approximately two thirds had a preference, with 57% of those choosing TCQ and 43% choosing MBCR.

大约三分之二的患者有偏好，其中57%选择了TCQ，43%选择了MBCR。

The remaining 36% were equally randomly assigned.

剩余的36%患者被等量随机分配。

Choosing a specific program or choosing to be randomly assigned had no significant effect on outcomes.

选择特定项目或选择随机分配对结果没有显著影响。

Both the combined random assignment and preference MBCR and TCQ groups improved more than their respective waitlists on TMD scores with small to medium effects.

随机分配的综合组和偏好组在TMD评分上均优于各自的等待名单组，改善效果从小到中等。

The largest improvements occurred for MBCR on subscales of tension, anger, and vigor and in TCQ on anger, depression, and vigor.

MBCR在紧张、愤怒和活力的子量表上以及TCQ在愤怒、抑郁和活力上的改善最为显著。

Conclusions

This large, pragmatic trial demonstrated both mindfulness and TCQ interventions improved mood in distressed cancer survivors, whether they chose a program or chose to be randomly assigned.

这项大型实用试验表明，无论是选择特定项目还是随机分配，正念和TCQ干预措施都能改善情绪困扰癌症幸存者的心情。